Clinical Trials Open to Healthy Volunteers

A “healthy volunteer” is someone who doesn't have any major health problems, and takes part in research to test new medicines, devices, or treatments. UCLA offers clinical trials on a wide range of medical conditions. Healthy volunteers can help UCLA researchers make better comparisons to better understand the treatment of diseases.

• Adaptation of the PCIP for Children Aged 6 to 11

  • study on Post-Traumatic Stress Disorder and Stress
  • open to healthy people ages 6-11

• Adaptive Intervention to Facilitate PrEP Uptake/Adherence Among Transgender Women

  • study on PrEP and Transgender Health
  • open to healthy males ages 18 years and up

• Adolescent PCIP Randomized Feasibility Trial

  • study on Post-Traumatic Stress Disorder and Stress
  • open to healthy people ages 12-22

• Aging and Reward System Response to Inflammation and Anxiety Study

  • study on Anhedonia and Inflammation
  • open to healthy people ages 60-80

• Alcoholic Liver Disease and the Gut Microbiome

  • study on Alcohol Use and Liver Disease
  • open to healthy people ages 18 years and up

• Allergic Disease Onset Prevention Study

  • study on Atopic Dermatitis (Eczema) and Type 1 Hypersensitivity
  • open to healthy people

• Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

  • study on Mild Cognitive Impairment and Alzheimer's Disease
  • open to healthy people ages 55-90

• American Lung Association (ALA) Lung Health Cohort

  • study on Lung Diseases
  • open to healthy people ages 25-35

• AMP SCZ® Observational Study: PREDICT-DPACC

  • study on Clinical High Risk and Psychotic Disorders
  • open to healthy people ages 12-30

• AnalgeSiC and appEtite-stimulating Effects of caNnabigerol and THC (ASCENT)

  • study on Pain and Appetite Loss
  • open to healthy people ages 21-55

• Analgesic and Subjective Effects of Terpenes

  • study on Pain and Drug Use
  • open to healthy people ages 21-55

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  • study on Frontotemporal Lobar Degeneration and Progressive Supranuclear Palsy
  • open to healthy people ages 18 years and up

• Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

  • study on Tuberous Sclerosis and Autism
  • open to healthy people ages 18 months and up

• Behavioral Weight Loss Intervention Utilizing Mobile Health Technology in Hematopoietic Stem Cell Transplant Patients

  • study on Obesity and Bone Marrow Transplant
  • open to healthy people ages 13-30

• Benzodiazepine Taper With Telehealth-Delivered Cognitive Behavioral Therapy for Patients Using Prescription Opioids

  • study on Substance Abuse and Anxiety
  • open to healthy people ages 18-85

• Biologic Therapy to Prevent Osteoarthritis After ACL Injury

  • study on ACL Injury and Immunotherapy
  • open to healthy people ages 18-35

• Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors

  • study on Astrocytoma and Glioblastoma
  • open to healthy people ages 18-80

• Boost Intentions and Facilitate Action to Promote COVID-19 Booster Take-up

  • study on COVID-19 and Vaccine
  • open to healthy people ages 18 years and up

• Brain Changes in Pediatric OSA

  • study on Sleep Apnea and Sleep Disorders
  • open to healthy people ages 7-12

• Brain Health in Breast Cancer Survivors

  • study on Cognitive Impairment and Cognition
  • open to healthy females ages 35-65

• Cannabis Effects as a Function of Sex (CanSex)

  • study on Pain and Drug Use
  • open to healthy people ages 21-55

• Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

  • study on CADASIL and Dementia
  • open to healthy people ages 18 years and up

• Childhood Cancer Survivor Study

  • study on Cancer, General
  • open to healthy people

• Clinic-Based Financial Coaching and Family Health and Development

  • study on Economic Problems and Child Development
  • open to healthy people ages 18 years and up

• Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

  • study on Genetic Diseases
  • open to healthy people ages 1 month to 100 years

• COMP-4 Supplementation and Brachial Artery FMD

  • study on Aging and Endothelial Dysfunction
  • open to healthy people ages 18-39

• Consent for Use of Stored Patient Specimens for Future Testing

  • study on HIV/AIDS
  • open to healthy people

• Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA

  • study on Osteoarthritis and Knee Replacement
  • open to healthy people ages 18 years and up

• Cortisol and Food Insecurity

  • study on Food Insecurity
  • open to healthy people ages 18 years and up

• Daily Habits & Consumer Preferences Study

  • study on Obesity
  • open to healthy people ages 18 years and up

• DBS Recordings to Characterize Movement Facilitation in Parkinson's Disease

  • study on Parkinson's Disease
  • open to healthy people ages 18 years and up

• Developing a Decision Instrument to Guide Abdominal-pelvic CT Imaging of Blunt Trauma Patients

  • study on Abdominal Injury and Pelvic Fracture
  • open to healthy people

• Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW

  • study on HIV/AIDS and Transgender Health
  • open to healthy males ages 16-29

• Discrimination and the Brain-Gut-Microbiome (BGM) Axis

  • study on Discrimination, Racial and Social Isolation
  • open to healthy females ages 18-50

• Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

  • study on Sleep and Alzheimer's Disease
  • open to healthy people ages 18 years and up

• Electronic Hookah and Endothelial Cell Function

  • study on Smoking Cessation and Endothelial Dysfunction
  • open to healthy people ages 21-39

• Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

  • study on Huntington's Disease
  • open to healthy people ages 18 years and up

• Expression of Stress Markers During Meth Treatment (EXPRESS+)

  • study on Substance Abuse and HIV/AIDS
  • open to healthy males ages 18-45

• Faith in Action! A Church-Based Navigation Model to Increase Breast Cancer Screening in Korean Women

  • study on Breast Cancer and Health Knowledge, Attitudes, Practice
  • open to healthy females ages 45-80

• Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History Study

  • study on Cerebellar Ataxia and Friedreich's Ataxia
  • open to healthy people

• Gastric Sleeve-Induced Weight Loss on Shortness of Breath in Obesity

  • study on Dyspnea and Quality of Life
  • open to healthy people ages 18 years and up

• GORE® CARDIOFORM Septal Occluder Migraine Clinical Study

  • study on Headache and Migraine
  • open to healthy people ages 18-55

• Healing Our Hearts Minds and Bodies: CVD Reduction in Persons With HIV

  • study on HIV/AIDS and Cardiovascular Disease
  • open to healthy people ages 18 years and up

• Health and Health Care Utilization Effects of Medical Debt Forgiveness

  • study on Health Care Utilization and Depression
  • open to healthy people ages 18 years and up

• Healthcare Providers as Trusted Messengers to Increase Receipt of Tax Credits Among Low-income Families

  • study on Depression and Child Development
  • open to healthy people ages 18-99

• Helping Families Pilot of a Family Resilience Program for Families Experiencing Homelessness

  • study on Family Relationship and Coping Skills
  • open to healthy people ages 8 years and up

• Immune Response and Safety of Various Potencies of an Investigational Chickenpox Vaccine Compared With a Marketed Chickenpox Vaccine, Given to Healthy Children 12 to 15 Months of Age

  • study on Chickenpox and Vaccine
  • open to healthy people ages 12 months to 15 months

• Implementation Research to Increase Colorectal Cancer Screening Rates Among Low Income and Ethnic Minority Groups

  • study on Colorectal Cancer and Cancer, General
  • open to healthy people ages 50-75

• Individuals With Autism and Germline Heterozygous PTEN Mutations

  • study on PTEN Hamartoma Tumor Syndrome and Autism
  • open to healthy people ages 18 months and up

• Inflammation in Methamphetamine and STIs (IMSTI)

  • study on Methamphetamines and Gonorrhea
  • open to healthy males ages 18 years and up

• Inflammatory Challenge Using Endotoxin

  • study on Alcohol Use and Inflammatory Response
  • open to healthy people ages 21-45

• Information Provision and Consistency Framing to Increase COVID-19 Booster Uptake

  • study on COVID-19 and Vaccine
  • open to healthy people ages 18 years and up

• Injectable DMAU for Male Contraception in Healthy Male Volunteers (CCN015)

  • study on Contraception
  • open to healthy males ages 18-50

• Insomnia Treatment and Cardiometabolic Health in Older Adults With Posttraumatic Stress Disorder

  • study on Post-Traumatic Stress Disorder and Insomnia
  • open to healthy people ages 55 years and up

• Intracranial Neurophysiological Signatures of Fear and Anxiety in Humans

  • study on Fear and GAD
  • open to healthy people ages 18-90

• Latino MSM Focused Pre-Exposure Prophylaxis Uptake Intervention

  • study on HIV/AIDS and PrEP
  • open to healthy males ages 18 years and up

• Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection

  • study on HIV/AIDS and PrEP
  • open to healthy people ages 16 years and up

• Longitudinal Early-onset Alzheimer's Disease Study Protocol

  • study on Alzheimer's Disease and Mild Cognitive Impairment
  • open to healthy people ages 40-64

• Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection

  • study on Gonococcal Infection and Vaccine
  • open to healthy people ages 18-50

• Metformin, a Drug Used to Treat Diabetes, vs Placebo

  • study on NIDDM and Obesity
  • open to healthy people ages 18 years and up

• mHealth to Enhance & Sustain Drug Use Reduction of the QUIT BI in Primary Care

  • study on Drug Use
  • open to healthy people ages 18 years and up

• Mindfulness Meditation Neuroimaging Study for Undergraduates

  • study on Inflammation and Psychosocial Functioning
  • open to healthy people

• MR Imaging and MR Spectroscopy of HIV

  • study on HIV/AIDS
  • open to healthy people ages 20-65

• Neural Correlates of Real World Spatial Navigation in Humans

  • study on Memory, Delayed
  • open to healthy people ages 18-90

• Non-invasive Brain Mapping of Movement Facilitation in Parkinson's Disease

  • study on Parkinson's Disease
  • open to healthy people ages 18 years and up

• Nutrition for Precision Health, Powered by the All of Us

  • study on Nutrition and Health
  • open to healthy people ages 18 years and up

• Obesity in Early Care and Education Settings

  • study on Obesity
  • open to healthy people ages 30 months and up

• Optimization of Prostate Biopsy - Micro-Ultrasound Versus MRI

  • study on Prostate Cancer
  • open to healthy males ages 18 years and up

• Optimizing PrEP Uptake and Adherence Among Male Sex Workers

  • study on PrEP
  • open to healthy males ages 18 years and up

• Orthodontic Varnish Microbiology Study

  • study on Cavities and Tooth Decay
  • open to healthy people ages 12-27

• Pancreatic Cancer Early Detection Consortium

  • study on Pancreatic Cancer and Pancreatic Cyst
  • open to healthy people ages 18-90

• Partners in Caring for Anxious Youth

  • study on Anxiety, Separation and Anxiety, Generalized
  • open to healthy people ages 7-17

• Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  • study on COVID-19 and High Blood Pressure
  • open to healthy people ages 0-20

• Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis

  • study on Stroke and Transient Ischemic Attack
  • open to healthy people ages 30 years and up

• Practice-Based Intervention To Improve Care for a Diverse Population Of Women With Urinary Incontinence

  • study on Urinary Incontinence
  • open to healthy people ages 18 years and up

• Probiotic Intervention Study

  • study on Obesity and Food Addiction
  • open to healthy people ages 18-50

• Project 1: Diet and Exercise Modulate the Sperm Epigenome in Men

  • study on Obesity
  • open to healthy males ages 18-40

• Prompt to Bundle COVID-19 Booster and Flu Shot

  • study on COVID-19 and Vaccine
  • open to healthy people ages 18 years and up

• Quantifying Body Composition and Liver Disease in Children Using Free-Breathing MRI and MRE

  • study on Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis
  • open to healthy people ages up to 40 years

• Regional Blocks for Lateral Condyle Fractures

  • study on Fractures, Closed and Humerus Fracture
  • open to healthy people ages 4-12

• Resources, Inspiration, Support and Empowerment (RISE) for Black Pregnant Women

  • study on Pregnancy and Depression
  • open to healthy females ages 18-65

• Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplants

  • study on End Stage Renal Disease and Kidney Disease
  • open to healthy people ages 18 years and up

• Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus (RSV) Vaccines RSV ΔNS2/Δ1313/I1314L, RSV 6120/ΔNS2/1030s, RSV 276 or Placebo, Delivered as Nose Drops to RSV-Seronegative Children 6 to 24 Months of Age

  • study on RSV and Vaccine
  • open to healthy people ages 6 months to 25 months

• Secondhand Effects of E-Hookah Aerosol

  • study on Hookah Smoking and Secondhand Aerosol
  • open to healthy people ages 21-49

• See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

  • study on Obesity and Malignant Neoplasm
  • open to healthy people ages 13-30

• Shared Decision Making Intervention for Diabetes Prevention in Women With a History of Gestational Diabetes Mellitus

  • study on Diabetes and Gestational Diabetes
  • open to healthy females ages 18-54

• Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma

  • study on Glioma and Brain Tumor
  • open to healthy people ages 18 years and up

• Sleep and Healthy Aging Research for Depression (SHARE-D) Study

  • study on Depression and Insomnia
  • open to healthy people ages 60-80

• Smoked THC and CBD in Men and Women

  • study on Drug Use and Intoxication by Drug
  • open to healthy people ages 21-55

• Social Support and Enhanced Fear Extinction

  • study on Fear and Anxiety
  • open to healthy people ages 18-55

• Social Support and Reduced Fear Acquisition

  • study on Fear and Anxiety
  • open to healthy people ages 18-55

• SPIROMICS Study of Early COPD Progression (SOURCE)

  • study on Chronic Obstructive Pulmonary Disease
  • open to healthy people ages 30-55

• Standard Endoscopic Hemostasis Versus OVESCO Severe Non-variceal UGI Hemorrhage

  • study on Upper Gastrointestinal Hemorrhage
  • open to healthy people ages 18-100

• Students Rising Above: Offsetting the Health and Mental Health Costs of Resilience

  • study on Internalizing Mental Health Symptoms and Allostatic Load
  • open to healthy people ages 13 years and up

• TACUNA (Traditions and Connections for Urban Native Americans)

  • study on Opioid Use and Alcohol Use
  • open to healthy people ages 18-25

• TEST-ON - Does iStim Reduce Urinary Urgency?

  • study on Overactive Bladder and Urgency-frequency Syndrome
  • open to healthy females ages 18-120

• Testing a Scalable Model For ACEs-Related Care Navigation

  • study on Adverse Childhood Experiences and Child Development
  • open to healthy people ages up to 11 years

• TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

  • study on Barrett's Esophagus and Esophageal Cancer
  • open to healthy people ages 18-100

• Treatment of Ocular Discomfort in Glaucoma Patients Using Multiple Topical Medications

  • study on Glaucoma and Ocular Surface Disease
  • open to healthy people

• TrialNet Pathway to Prevention of T1D

  • study on Diabetes and Diabetes Type 1
  • open to healthy people ages 30 months to 45 years

• UCLA Perinatal Biospecimen Repository

  • study on Pregnancy
  • open to healthy people

• UCLA REST Study (REsearch on Sleep Techniques)

  • study on Sleep Disorders and Inflammation
  • open to healthy people ages 18-20

• Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

  • study on Breast Cancer and Lung Cancer
  • open to healthy people ages 40-80

• Validation of Ejection Fraction and Cardiac Output Using Biostrap Wristband

  • study on Heart Failure
  • open to healthy people ages 18 years and up

• Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

  • study on Breast Cancer and Cancer, General
  • open to healthy females ages 40-74

• Writing About Experiences and Health in Older Adults II

  • study on Social Psychology
  • open to healthy people ages 65 years and up

Current as of: November 30, 2023