Recording of Intraoperative Spinal Cord Stimulation and Monitoring

a study on Cervical Stenosis Disk, Herniated Spondylosis

Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Los Angeles, California
Dates
study started
completion around
Principal Investigator
by Daniel Lu, MD, PhD

Description

Summary

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.

Keywords

Cervical Stenosis, Disk, Herniated, Spondylosis, Intervertebral Disc Displacement, epidural electrical stimulation

Eligibility

You can join if…

Open to people ages 18 years and up

  • Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized.

You CAN'T join if...

  • none

Location

  • University of California, Los Angeles accepting new patients
    Los Angeles California 90095 United States

Lead Scientist at UCLA

  • Daniel Lu, MD, PhD
    Professor, Neurosurgery, Medicine. Authored (or co-authored) 100 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT05356286
Study Type
Interventional
Participants
Expecting 150 study participants
Last Updated