Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)
Tumor, Tumor, Solid, Metastasis, Metastatic Cancer, Cancer, Cancer Metastatic, Tumors, Neoplasms, Neoplasm Metastasis, Solid Tumor, Advanced Solid Tumor, Advanced Cancer, Malignant Solid Tumor, Malignant Solid Neoplasm, Malignant Neoplasm, Malignant Tumor, TSC, TSC1, TSC2, Metastatic Solid Tumor, Metastatic Neoplasm, TSC1 gene, TSC2 gene, Tissue agnostic, Basket, nab-sirolimus, mTOR inhibitor, nanoparticle albumin bound, mammalian target of rapamycin, mechanistic target of rapamycin, tumor profile, tuberous sclerosis complex 1, tuberous sclerosis complex 2, mTOR, sirolimus, ABI-009, FYARRO, Precision, Precision 1, Pathogenic alterations, Pathogenic mutations, Inactivating mutations, Pathogenic inactivating TSC1 alterations, Pathogenic inactivating TSC2 alterations
Lead Scientist at UCLA
- Noah Federman, MD
Dr. Noah Federman is the Director of the Pediatric Bone and Soft Tissue Sarcoma Program at UCLA, part of the UCLA Sarcoma Program and UCLA's Jonsson Comprehensive Cancer Center. Dr. Federman specializes in treating children, adolescents and young adults with these aggressive cancers.