for people ages 18 years and up (full criteria)
at Los Angeles, California
study started
completion around
Principal Investigator
by Steven J Shoptaw, PhD



With over 72,000 overdose deaths in 2017, of which 47,600 are attributable to opioid overdose, the opioid epidemic has become North America's most widespread behavioral public health problem. Medication-assisted treatment (MAT) for opioid use disorder (OUD) is highly efficacious. The Opioid Addiction Recovery Support (OARS), comprised of a healthcare team portal connected to a patient mobile application, provides opioid-related education, promotes connectedness with clinicians, and tracks MAT treatment progress. This study will conduct interviews with patients that will inform optimal design of OARS, assess the efficacy of OARS in improving MAT outcomes in primary care settings, and evaluate the sustainability and return on investment.

It joins an outstanding scientific team at University of California, Los Angeles and a small business that has developed, Opioid Addiction Recovery Support (OARS) -- a software platform that by integrating with the Electronic Health Record (EHR) improves clinical management of patients by primary care providers (PCPs) treating patients with OUD using MAT. OARS platform uses a dashboard to show the real-time measurement of patient achievements in recovery. It provides opportunities for patients to interact with their PCPs, allowing for better connection to and support from their PCPs. OARS platform features artificial intelligence to analyze information from the EHR and from patients to provide a relapse risk assessment for patients receiving MAT for OUD, an innovation that sets OARS apart from other software solutions. The goal of Phase 1 was to modify the OARS platform for use in primary care settings by conducting interviews with Primary Care Physicians (PCPs) (N=20) and their patients with OUD (N=40) in primary care settings to collect data on feasibility and acceptability of engaging with OARS to inform the user-centered design of OARS.

The goals of Phase 2 of this study are to: (1) to assess the effectiveness of OARS in improving opioid agonist treatment outcomes across 6 treatment programs (N=200 treated patients) and (2) evaluate the sustainability and return on investment of OARS implementation across 6 treatment programs. A commercialization plan documents progress to date for the OARS platform and presents a market plan to improve both the scale and quality of MAT services delivered by PCPs in primary care, which is a major contribution to addressing the ongoing opioid epidemic.

Official Title

Technology Improving Success of Medication-Assisted Treatment in Primary Care - Phase 2


Opioid-use Disorder, Opioid use disorder, Primary care, mHealth, Medication for opioid use disorder, Technological solutions, Opioid-Related Disorders, Opioid Analgesics, Opioid Addiction Recovery Support Software Platform, Opioid Addiction Recovery Support (OARS)


You can join if…

Open to people ages 18 years and up

  • For Primary Care Providers (PCPs):
    • Physician, nurse practitioner, or physician's assistant in any area within primary care;
    • In possession of valid DATA-2000 waiver;
    • Currently treating more than two patients with OUD using oral buprenorphine-naloxone product;
    • Willing to distribute study materials to their patients describing the research and providing options for their participation.
  • For Patient participants:
    • Diagnosed and treated using MAT within primary care setting (i.e., family medicine, internal medicine, adolescent medicine, pediatrics, obstetrics/gynecology, geriatrics, infectious diseases, emergency department, non-cancer pain management).

You CAN'T join if...

  • For PCPs:
    • Specialization outside primary care (e.g., psychiatry, neurology, etc) or provider works in specialized setting (e.g., addiction treatment programs; mental health clinic);
    • Not treating patients with OUD with oral buprenorphine-naloxone product (e.g., long-acting naltrexone or buprenorphine injections);
    • Individual interviews with physicians and their patients to discuss initially barriers and challenges to MAT for patients with OUD seen in primary care settings.
  • For Patient participants:
    • MAT delivered in specialty care settings (i.e., psychiatry, substance abuse treatment programs).


  • UCLA Center for Behavioral and Addiction Medicine
    Los Angeles California 90024 United States

Lead Scientist at UCLA


accepting new patients by invitation only
Start Date
Completion Date
Q2i, LLC
Further information about the OARS solution available here.
Study Type
Expecting 200 study participants
Last Updated