Summary

Eligibility
for people ages 18 years and up (full criteria)
Location
at Santa Monica, California
Dates
study started
completion around
Principal Investigator
by Eric J Kezirian, MD, MPH

Description

Summary

Prospective, interventional cohort study of drug-induced sleep endoscopy (DISE) to evaluate the upper airway in a cohort of obstructive sleep apnea (OSA) surgical patients. This study has investigated the reliability of this technique, demonstrating moderate-substantial interrater and test-retest reliability. This research has also compared DISE findings to those of the lateral cephalogram X-ray and examined DISE findings in individuals who have not responded to previous sleep apnea surgery. These papers have been published and available through PubMed. Additional research is ongoing, with examination of DISE findings, comparison to other evaluation techniques, and the association between DISE findings and surgical outcomes.

Keywords

Sleep Apnea, Obstructive, Obstructive Sleep Apnea, Propofol, Sleep Endoscopy, Apnea, Sleep Apnea Syndromes, Propofol sedation

Eligibility

You can join if…

Open to people ages 18 years and up

  • Adult patients with OSA considering surgical treatment

You CAN'T join if...

  • Minors
  • Pregnant women
  • Patients unable to provide informed consent in English themselves
  • Prisoners
  • Allergy to propofol, soybean oil, egg lecithin or glycerol
  • Other contraindication to use of propofol (decision of anesthesiologist or otolaryngologist.)

Location

  • UCLA Santa Monica Medical Center accepting new patients
    Santa Monica California 90401 United States

Lead Scientist at UCLA

  • Eric J Kezirian, MD, MPH
    Eric Kezirian has a clinical and research focus in the surgical evaluation and treatment of obstructive sleep apnea and snoring.

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT00695214
Phase
Phase 2 research study
Study Type
Interventional
Participants
Expecting 800 study participants
Last Updated