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YAP1 or TAZ Gene Fusions clinical trials at UCLA

1 in progress, 0 open to eligible people

Showing trials for
  • Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects With Advanced Solid Tumors

    Sorry, not currently recruiting here

    This is a Phase 1, first-in-human (FIH) clinical study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary antitumor activity of IK-930, an oral TEAD inhibitor, administered orally (PO) as monotherapy in subjects with advanced solid tumors with or without gene alterations in the Hippo pathway for whom there are no further treatment options known to confer clinical benefit. The study consists of two phases, an initial Dose Escalation phase followed by a Dose Expansion phase.

    Los Angeles, California and other locations

Our lead scientists for YAP1 or TAZ Gene Fusions research studies include .

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