A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
Solid Tumor, Adult, Solid Tumor, Pancreatic Cancer, Pancreatic Neoplasms, Pancreas Cancer, Non Small Cell Lung Cancer, Non Small Cell Lung Cancer Recurrent, Non-Small Cell Squamous Lung Cancer, NSCLC, NSCLC, Recurrent, Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenocarcinoma, CRC, Colorectal Cancer Metastatic, Cancer, CAR T Cell, Solid Tumors, autologous, T cell, Carcinoembryonic Antigen, CEA, HLA-A2, Solid Tumors Expressing CEA, PANC, Non-Small Cell Lung Cancer, Neoplasms, Lung Neoplasms, Non-Small-Cell Lung Carcinoma, Recurrence, xT-Onco with HLA-LOH Assay
Lead Scientist at UCLA
- J. Randolph Hecht, MD
Dr. Joel R. Hecht holds the Carol and Saul Rosenzweig Endowed Chair for Cancer Therapies Development.