Summary

Eligibility
for people ages 18-65 (full criteria)
Location
at Los Angeles, California
Dates
study started
completion around
Principal Investigator
by Itzhak Fried

Description

Summary

The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by application of auditory and electrical stimulations during sleep and its effect on modulating memory processes.

Keywords

Memory, Delayed, sleep, stimulation, memory, learning, single-unit, Auditory and Electrical Stimulation

Eligibility

You can join if…

Open to people ages 18-65

  • All epilepsy patients between the ages of 18 and 65 who undergo depth electrode placement for clinical purposes
  • Eligibility is determined by the epilepsy surgery team (based on neuropsychological testing and on psychiatric evaluation)
  • Willing to provide informed consent and participate the study

You CAN'T join if...

  • Neurological or psychiatric issues, other than epilepsy, that would put the patient at risk
  • Patient is younger than 18 or older than 65 years of age
  • Unwilling to provide informed consent

Location

  • University of California Los Angeles accepting new patients
    Los Angeles California 90095 United States

Lead Scientist at UCLA

  • Itzhak Fried
    Professor-in-Residence, Neurosurgery, Medicine. Authored (or co-authored) 200 research publications

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, Los Angeles
ID
NCT05452122
Study Type
Interventional
Participants
Expecting 150 study participants
Last Updated