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Spinal Cord Injury clinical trials at UCLA

5 in progress, 3 open to eligible people

Showing trials for
  • Neuromodulation to Improve Respiratory Function in Cervical Spinal Cord Injury

    open to eligible people ages 18-75

    This is a phase 1 study of safety and feasibility of cervical spinal cord stimulator implantation in cervical SCI subjects who are ventilator dependent. The Investigators will be focusing on the safety and feasibility of this approach. Participants may qualify for the study if they are male or female 18-75 years old, are at least 1 year after original injury, have injury at C2 to C7 level, and dependent on mechanical ventilation to help them breathe. Additionally, they need to be able to attend up to twice weekly testing sessions for up to 21 months.

    Los Angeles 5368361, California 5332921 and other locations

  • Visuomotor Prosthetic for Paralysis

    open to eligible people ages 22-65

    The investigators objective is to run human clinical trials in which brain activity recorded through a "brain-chip" implanted in the human brain can be used to provide novel communication capabilities to severely paralyzed individuals by allowing direct brain-control of a computer interface. A prospective, longitudinal, single-arm early feasibility study will be used to examine the safety and effectiveness of using a neural communication system to control a simple computer interface and a tablet computer. Initial brain control training will occur in simplified computer environments, however, the ultimate objective of the clinical trial is to allow the human patient autonomous control over the Google Android tablet operating system. Tablet computers offer a balance of ease of use and functionality that should facilitate fusion with the BMI. The tablet interface could potentially allow the patient population to make a phone call, manage personal finances, watch movies, paint pictures, play videogames, program applications, and interact with a variety of "smart" devices such as televisions, kitchen appliances, and perhaps in time, devices such as robotic limbs and smart cars. Brain control of tablet computers has the potential to greatly improve the quality of life of severely paralyzed individuals. Five subjects will be enrolled, each implanted with the NCS for a period of at least 53 weeks and up to 313 weeks. The study is expected to take at least one year and up to six years in total.

    Los Angeles 5368361, California 5332921 and other locations

  • Improving Bladder Function in SCI by Neuromodulation

    open to eligible males ages 18-45

    This trial will investigate the safety and utility of spinal cord neuromodulation to improve urinary bladder function in the context of spinal cord injury.

    Los Angeles 5368361, California 5332921

  • Spinal Cord Neuromodulation for Spinal Cord Injury

    Sorry, in progress, not accepting new patients

    This study is designed to assess the strategy of using spinal cord stimulation to improve the ability to move in spinal cord injured humans.

    Los Angeles 5368361, California 5332921

  • Telerehabilitation Early After CNS Injury

    Sorry, in progress, not accepting new patients

    The goal of this clinical trial is to assess the safety and feasibility of providing extra doses of rehabilitation therapy for persons with a recent stroke, traumatic brain injury (TBI) and/or spinal cord injury (SCI). The therapy treatment targets to improve arm function by introducing telerehabilitation to the bedside of participants during the inpatient rehab admission period. Participants will use a newly developed functional training system (HandyMotion) to access therapy treatment program directly from their hospital room. HandyMotion is a sensor-based training system that can connect to the TV set in the hospital room, enabling patients to access their therapy training program to practice rehab-oriented games and exercises ad libitum, at any time of the day.

    Los Angeles 5368361, California 5332921 and other locations

Our lead scientists for Spinal Cord Injury research studies include .

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