PrEP clinical trials at UCLA

4 in progress, 2 open to eligible people

Showing trials for

  • EASE: The Materna Prep Pivotal Study

    open to eligible females ages 18 years and up

    This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery. Subjects are randomized to Materna Prep Device or Standard of Care without use of the Materna Prep Device Intervention with the Materna Prep Device is expected to be a one-time use of approximately 30-90 minutes during the 1st stage of labor. Subject participation in the study is targeted to be 12 months from the time of the use of the device during delivery.

    Los Angeles, California and other locations

  • Optimizing PrEP Uptake and Adherence Among Male Sex Workers

    open to eligible males ages 18 years and up

    "PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers (MSW)

    Los Angeles, California and other locations

  • ON-DEMAND PREP FORMULATIONS COMPARING RECTAL AND ORAL TENOFOVIR

    Sorry, not currently recruiting here

    This is a Phase 2, multi-site, two-period, open label randomized crossover (Period 1 and 2) study. Participants are randomized 1:1 to one of two 8-week on-demand product sequences - TFV douche then oral F/TDF or oral F/TDF then TFV douche - with a 2 to 4-week washout period in between. Domains of safety, acceptability, adherence, and PK/PD (sub-study only) are assessed for each product.

    Los Angeles, California and other locations

  • Lenacapavir for HIV Pre-Exposure Prophylaxis in People Who Are at Risk for HIV Infection

    Sorry, in progress, not accepting new patients

    The goal of this clinical study is to test how well the study drug, lenacapavir (LEN), works in preventing the risk of HIV.

    Los Angeles, California and other locations

Our lead scientists for PrEP research studies include .

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