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Lennox-Gastaut Syndrome clinical trials at UCLA

3 in progress, 0 open to eligible people

Showing trials for
  • Intermediate-Size Expanded Access Protocol (EAP) for LP352

    Sorry, not accepting new patients

    This is an intermediate-size expanded access program (EAP) study. The purpose of this EAP is to provide continued access to LP352, an investigational drug product being investigated in participants with DEEs. The EAP study will allow continued treatment with LP352 for eligible participants diagnosed with treatment resistant DEEs who successfully completed an LP352 Clinical Trial (Enrollment by Invitation) or an immediate family member who has the exact same gene mutation resulting in the same DEE epilepsy syndrome phenotype or a patient who previously participated in the lorcaserin EAP.

    Los Angeles 5368361, California 5332921 and other locations

  • Soticlestat as an Add-on Therapy in Children and Adults With Dravet Syndrome or Lennox-Gastaut Syndrome

    Sorry, in progress, not accepting new patients

    The main aim of the study is to learn if soticlestat, when given as an add-on therapy, reduces the number of seizures in children and adults with Dravet Syndrome (DS) or Lennox-Gastaut Syndrome (LGS). Participants will receive their standard anti-seizure therapy, plus tablets of soticlestat. There will be scheduled visits and follow-up phone calls throughout the study.

    Los Angeles 5368361, California 5332921 and other locations

  • LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)

    Sorry, accepting new patients by invitation only

    This (DEEp OLE Study) is a multicentre, open-label study to investigate the long-term safety, efficacy, tolerability, and pharmacokinetics (PK) of LP352 in the treatment of seizures in children and adults with DEE who completed Study LP352-301 or LP352-302. The study consists of 3 main phases: Screening, Titration period and Maintenance period, followed by a Taper period and Follow-Up. The total duration of the study will be approximately 14 months.

    Los Angeles 5368361, California 5332921 and other locations

Our lead scientists for Lennox-Gastaut Syndrome research studies include .

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