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Essential Thrombocythemia clinical trials at UCLA

2 in progress, 0 open to eligible people

Showing trials for
  • CPI-0610 With and Without Ruxolitinib in Patients With Myelofibrosis

    Sorry, in progress, not accepting new patients

    Phase 1 Part (Complete): Open-label, sequential dose escalation study of pelabresib in patients with previously treated Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic/Myeloproliferative Neoplasms, and Myelofibrosis. Phase 2 Part: Open-label study of CPI-0610 with and without Ruxolitinib in patients with Myelofibrosis. CPI-0610 is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins.

    Los Angeles, California and other locations

  • Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2)

    Sorry, in progress, not accepting new patients

    A Phase 3, randomized, blinded study comparing pelabresib (CPI-0610) and ruxolitinib with placebo and ruxolitinib in myelofibrosis (MF) patients that have not been previously treated with Janus kinase inhibitors (JAKi). Pelabresib is a small molecule inhibitor of bromodomain and extra-terminal (BET) proteins.

    Los Angeles, California and other locations

Our lead scientists for Essential Thrombocythemia research studies include .

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