End Stage Renal Disease clinical trials at UCLA
8 in progress, 5 open to eligible people
Comparing Surgical and Endovascular Arteriovenous Fistula Creation
open to eligible people ages 18-99
Patients with end-stage kidney disease (ESKD) who use hemodialysis to filter their blood require vascular access for the dialysis machine; the most common type of vascular access is called an arteriovenous fistula (AVF). The AVF is a direct connect…
Los Angeles, California and other locations
Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study
open to eligible people ages 18-70
The goal of this clinical trial is to demonstrate the feasibility of bladder transplantation in patients with terminal bladder diseases who would benefit from a new bladder or a combined kidney and bladder transplant. The main questions it aims to…
Los Angeles, California
Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplants
open to eligible people ages 18 years and up
The study seeks to determine if patients with a pre-existing, well-functioning kidney transplant from a HLA-identical living donor can be withdrawn from immunosuppressive medications without compromising allograft function through hematopoietic stem …
Los Angeles, California
Arteriovenous Vascular (AV) ACCESS Trial
open to eligible people ages 60 years and up
This study is to prospectively compare the effectiveness and safety of the two types of arteriovenous access placement (fistula or graft) in older adults with end stage kidney disease and multiple chronic conditions
Los Angeles, California and other locations
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
open to eligible people ages 18 years and up
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
Sylmar, California and other locations
Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis
Sorry, in progress, not accepting new patients
The main purpose of this study is to compare the Human Acellular Vessel (HAV) with arteriovenous fistula (AVF) when used for hemodialysis access
Sylmar, California and other locations
Immunological Tolerance in Patients With Mismatched Kidney Transplants
Sorry, in progress, not accepting new patients
This study seeks to determine if administration of the drug belumosudil (KD025) will be safe and improve transplant tolerance in subjects undergoing combined Human Leukocyte Antigen (HLA) single haplotype-matched related or 0-3 antigen (at A, B, C,…
Los Angeles, California
VIRTUUS Children's Study
Sorry, in progress, not accepting new patients
The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.
Los Angeles, California and other locations
Our lead scientists for End Stage Renal Disease research studies include Karen Woo, MD, PhD Nima Nassiri, MD Warren Chow, MD Mark Archie, MD Jeffrey L. Veale, MD.
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