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End Stage Renal Disease clinical trials at UCLA

8 in progress, 5 open to eligible people

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  • Comparing Surgical and Endovascular Arteriovenous Fistula Creation

    open to eligible people ages 18-99

    Patients with end-stage kidney disease (ESKD) who use hemodialysis to filter their blood require vascular access for the dialysis machine; the most common type of vascular access is called an arteriovenous fistula (AVF). The AVF is a direct connect…

    Los Angeles, California and other locations

  • Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

    open to eligible people ages 18-70

    The goal of this clinical trial is to demonstrate the feasibility of bladder transplantation in patients with terminal bladder diseases who would benefit from a new bladder or a combined kidney and bladder transplant. The main questions it aims to…

    Los Angeles, California

  • Retro-active Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-identical Kidney Transplants

    open to eligible people ages 18 years and up

    The study seeks to determine if patients with a pre-existing, well-functioning kidney transplant from a HLA-identical living donor can be withdrawn from immunosuppressive medications without compromising allograft function through hematopoietic stem …

    Los Angeles, California

  • Arteriovenous Vascular (AV) ACCESS Trial

    open to eligible people ages 60 years and up

    This study is to prospectively compare the effectiveness and safety of the two types of arteriovenous access placement (fistula or graft) in older adults with end stage kidney disease and multiple chronic conditions

    Los Angeles, California and other locations

  • Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry

    open to eligible people ages 18 years and up

    Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,

    Sylmar, California and other locations

  • Human Acellular Vessel (HAV) With Fistulas as Conduits for Hemodialysis

    Sorry, in progress, not accepting new patients

    The main purpose of this study is to compare the Human Acellular Vessel (HAV) with arteriovenous fistula (AVF) when used for hemodialysis access

    Sylmar, California and other locations

  • Immunological Tolerance in Patients With Mismatched Kidney Transplants

    Sorry, in progress, not accepting new patients

    This study seeks to determine if administration of the drug belumosudil (KD025) will be safe and improve transplant tolerance in subjects undergoing combined Human Leukocyte Antigen (HLA) single haplotype-matched related or 0-3 antigen (at A, B, C,…

    Los Angeles, California

  • VIRTUUS Children's Study

    Sorry, in progress, not accepting new patients

    The objective of the VIRTUUS Children's Study is to adapt identified and validated adult noninvasive diagnostic and prognostic biomarkers for the characterization of allograft status in pediatric recipients of kidney allografts.

    Los Angeles, California and other locations

Our lead scientists for End Stage Renal Disease research studies include .

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