Chronic Obstructive Pulmonary Disease clinical trials at UCLA

11 in progress, 4 open to eligible people

Showing trials for

  • Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)

    open to eligible people ages 30 years and up

    The purpose of this study is to determine if doxycycline will reduce progression of emphysema in people living with HIV. The secondary objectives are to examine the effects of doxycycline on change in quantity of emphysema, six minute walk distance, …

    Los Angeles, California and other locations

  • Clean Air Randomized Controlled Trial in COPD

    open to eligible people ages 40 years and up

    This is a multi-center randomized, sham-controlled clinical trial to determine the effectiveness of an air cleaner intervention aimed at improving indoor air quality on reducing COPD exacerbation risk and improving quality of life, functional…

    Los Angeles, California and other locations

  • Revefenacin in Acute Respiratory Insufficiency in COPD

    open to eligible people ages 40 years and up

    RARICO is a pragmatic, randomized, controlled, double-blinded, multi-center trial evaluating the safety and feasibility of nebulized revefenacin in comparison to nebulized ipratropium in patients with COPD and acute respiratory failure requiring…

    Los Angeles, California and other locations

  • SPIROMICS Study of Early COPD Progression (SOURCE)

    open to eligible people ages 30-55

    This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals. The study has three main goals: - To use CT scan imaging to identify which…

    Los Angeles, California and other locations

  • Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD).

    Sorry, not currently recruiting here

    This study will investigate the effect of Budesonide, Glycopyrronium, and Formoterol Fumarate (BGF) metered dose inhaler (MDI) compared with Placebo MDI, and Budesonide and Formoterol Fumarate (BFF) MDI on isotime inspiratory capacity (IC) and…

    Los Angeles, California and other locations

  • RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

    Sorry, in progress, not accepting new patients

    This is a prospective, randomized, parallel group, double-blind, sham-controlled, multicenter clinical trial following patients to 2 years. The objective is to assess the safety and effectiveness of Bronchial Rheoplasty for the treatment of the…

    Torrance, California and other locations

  • TLD in Patients with COPD

    Sorry, in progress, not accepting new patients

    The purpose of this study is to confirm the safety and efficacy of the Nuvaira Lung Denervation System (Nuvaira System) in the treatment of COPD.

    Torrance, California and other locations

  • Mechanistic Study of the Effect of Itepekimab on Airway Inflammation in Patients With COPD

    Sorry, in progress, not accepting new patients

    This study is an exploratory, two-part, 12-week, Phase 2a study to evaluate the mechanism of action of Itepekimab (anti-IL-33-mAb) and its impact on airway inflammation in former and current smokers with COPD, aged 40 to 70 years. This study…

    Torrance, California and other locations

  • SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

    Sorry, in progress, not accepting new patients

    Phase 2 study to compare SAR447537 (INBRX-101) to plasma derived A1PI therapy in adults with AATD emphysema

    Los Angeles, California and other locations

  • PiMZ Longitudinal Cohort (PiMZ Logic)

    Sorry, not yet accepting patients

    Alpha-1 Anti-trypsin Deficiency (AATD) is a genetic disease with lung and liver disease presentations. Presentations are variable in the heterozygous population, the most predominant genotype being PiMZ. The purpose of this study in PiMZ…

    Los Angeles, California and other locations

  • COPD Subgroups and Biomarkers

    Sorry, in progress, not accepting new patients

    SPIROMICS I and SPIROMICS II are observational studies of Chronic Obstructive Pulmonary Disease (COPD). SPIROMICS I had two main aims: (1) To find groups of patients with COPD who share certain characteristics; (2) To find new ways of measuring…

    Los Angeles, California and other locations

Our lead scientists for Chronic Obstructive Pulmonary Disease research studies include .

Last updated: