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CDKL5 Deficiency Disorder clinical trials at UCLA

4 in progress, 1 open to eligible people

Showing trials for
  • International CDKL5 Clinical Research Network

    open to eligible people ages 1 month to 100 years

    Pathogenic variants in the Cyclin-dependent kinase like 5 (CDKL5) gene cause CDKL5 deficiency disorder (CDD, MIM 300672, 105830), a severe developmental and epileptic encephalopathy associated with cognitive and motor impairments and cortical visual …

    Los Angeles, California and other locations

  • Soticlestat in Adults and Children With Rare Epilepsies

    Sorry, in progress, not accepting new patients

    The main aim is to assess the long-term safety and tolerability of soticlestat when used along with other anti-seizure treatment. Participants will receive soticlestat twice a day. Participants will visit the study clinic every 2-6 months throughout …

    Los Angeles, California and other locations

  • ZX008 in Subjects With CDKL5 Deficiency Disorder

    Sorry, in progress, not accepting new patients

    This is a multicenter, double-blind, parallel-group, placebo controlled, 2-part study to evaluate the efficacy and safety of ZX008 when used as adjunctive therapy for the treatment of uncontrolled seizures in children and adults with…

    Los Angeles, California and other locations

  • Observational Study in Patients with Cyclin-dependent Kinase-like 5 Deficiency Disorder

    Sorry, in progress, not accepting new patients

    Observational, noninterventional, 3-year study to examine the presence of detectable differences in neurocognitive, developmental, motor, neurophysiologic, and quality of life measures over time in patients with cyclin-dependent kinase-like 5…

    Los Angeles, California and other locations

Our lead scientists for CDKL5 Deficiency Disorder research studies include .

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